Statistics

1. Basic statistics information

ItemStatistic
eccDNAs1270
eccDNA genes (counted by ensembl ID)54901
eccDNA-containing sample types8
Total sample types11
eccDNA-containing tissue types26
Total tissue types30
eccDNA-containing diseases/cancers42
Total diseases/cancers57
eccDNA size21 bp ~ 1024 Mb
eccDNA copy count1 ~ 160.2
Segments per eccDNA1 ~ 99
eccDNA genes per eccDNA0 ~ 19697

2. Distribution of eccDNAs based on sample types

Sample typeCount
TP3014
TM152
Cancer tissue65
Cancer cell line63
TB40
Cancer PDX25
Cell culture16
Unspecified10
TR6
Circulating tumor cells2
FFPE2

3. Distribution of eccDNAs based on tissue types

Tissue typeCount
Prostate307
Blood256
Liver252
Pancreas221
Kidney206
Bronchus and lung193
Pediatric brain188
Brain187
Breast180
Skin173
Head and neck164
Stomach147
Corpus uteri143
Thyroid139
Bladder112
Esophagus112
Colon91
Ovary83
Cervix uteri66
Eye and adnexa50
Bone37
Retroperitoneum and peritoneum36
Unspecified16
Lung15
Biliary tract11
Hematopoietic_tissue6
Central_nervous_system1
Haematopoietic_and_lymphoid_tissue1
Omentum1
Soft_tissue1

4. Distribution of eccDNAs based on chromosomes

# chromosomes# eccDNAs
1 chr1015
2 chrs128
3 chrs50
4 chrs29
5 chrs15
6 chrs12
7 chrs4
8 chrs6
9 chrs2
10 chrs2
11 chrs2
12 chrs3
14 chrs1
19 chrs1
Chromosome# eccDNA
chr142
chr226
chr328
chr415
chr514
chr635
chr7310
chr8164
chr920
chr1073
chr11101
chr1241
chr1313
chr149
chr159
chr166
chr1754
chr189
chr1911
chr2019
chr213
chr229
chrX4
multiChrs255

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Peng, L. et al. eccDNAdb: a database of extrachromosomal circular DNA profiles in human cancers. Oncogene (2022).